Quinolines and derivatives
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Filtered Search Results
eMolecules DBCO amine | Chem-Impex | 1255942-06-3 | MFCD22380759 | 276.339 | C18H16N2O | 99.000 | NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 100mg | 603112390
DBCO amine | Chem-Impex | 1255942-06-3 | MFCD22380759 | 276.339 | C18H16N2O | 99.000 | NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 100mg | 603112390
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Apexbio Technology LLC Imiquimod 99011-02-6 100mg
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Imiquimod (CAS 99011-02-6) is a small-molecule agonist targeting Toll-like receptor 7 (TLR7) It is designed to activate TLR7 thereby modulating innate immune responses Imiquimod exerts its biological activity primarily through induction of cytokines such as interferon-gamma and interleukin-12 while suppressing IL-4 and IL-5 thus affecting cellular immunity In in vitro studies imiquimod demonstrates TLR7 activation with an EC50 of approximately 2 1 M and exhibits an anti-proliferative effect mediated by opioid growth factor (OGF) with an IC50 of 2 M Based on these pharmacological properties imiquimod holds research potential in cancer inflammatory diseases and dermatologic conditions including basal cell carcinoma superficial squamous cell carcinoma actinic keratosis and external genital warts
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Apexbio Technology LLC SB743921 940929-33-9 200mg
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SB743921 (CAS 940929-33-9) is a potent and selective inhibitor of kinesin spindle protein (KSP) exhibiting a Ki of 0 1 nM for human KSP and 0 12 nM for mouse KSP with negligible affinity for other kinesins By targeting KSP SB743921 disrupts mitotic spindle formation leading to cell cycle arrest and apoptosis In cellular assays SB743921 demonstrates strong antiproliferative activity against SKOV3 Colo205 MV522 and MX1 cell lines with IC50 values ranging from 0 02 to 1 7 nM Additionally it shows efficacy in multiple human tumor xenograft models and in a murine P388 lymphocytic leukemia model SB743921 is utilized in oncology research for mechanistic studies and therapeutic evaluation of mitotic inhibition
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000366168 GW 4064 200MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000366039 DACOMITINIB 200MG
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TARGETMOL CHEMICALS INC 4-Nitroquinoline 1-oxide 1G
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Also available in 1 mL, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. 4-Nitroquinoline 1-oxide (4-NQO) is a chemical carcinogen that induces mutations in bacteria, fungi, and animals through the formation of large amounts of purine adducts. Purity 98.06%
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Cambridge Isotope Laboratories 1 2 4 5 8-PentaCN (PCN-59) (unlabeled) 100 ug/mL in nonane 1 mL
1 2 4 5 8-PentaCN (PCN-59) (unlabeled) 100 ug/mL in nonane 1 mL
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Medchemexpress LLC 9-(oxolan-2-yl)purin-6-amine | 17318-31-9 | MFCD00210216 | ≥98.0% | 205.22 g/mol | C9H11N5O | 200 MG
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SQ22536 is a small-molecule adenylate cyclase inhibitor used in research to modulate cAMP signaling. It is provided as a powder and is characterized by CAS 17318-31-9, molecular formula C9H11N5O, and molecular weight 205.22 g/mol. The compound is suitable for laboratory-scale in vitro and in vivo studies with documented solubility and storage recommendations.
- Potent adenylate cyclase inhibitor for cAMP pathway studies.
- Suitable for in vitro and in vivo applications with established vehicle formulations.
- Soluble in DMSO and water at experimentally useful concentrations.
- Stable as a powder under cold storage with multi-year shelf life.
- Provided as an analytical standard for research use only.
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Apexbio Technology LLC Diosmetin 520-34-3 200mg
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Diosmetin (CAS 520-34-3) is a small molecule flavonoid that functions as an agonist of the aryl hydrocarbon receptor (AHR) a ligand-activated transcription factor involved in the regulation of xenobiotic-metabolizing enzymes In cell-based studies diosmetin dose-dependently increases AHR-mediated transcriptional activation including upregulation of CYP1A1 mRNA and enzymatic activity in MCF-7 cells The compound demonstrates inhibitory effects on CYP1A1 enzyme activity with an IC50 of approximately 30 nM in microsomal assays Diosmetin is utilized in biomedical research to study AHR activation CYP1 enzyme regulation and related cellular responses such as viability and gene expression changes
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5000371277 GSK269962A 200MG
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Selleck Chemical LLC STF-31
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STF-31 is a selective glucose transporter GLUT1 inhibitor
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000362507 NLRP3-IN-11 200MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000366080 DEUCRAVACITINIB 200MG
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5000366064 INFIGRATINIB 200MG
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5000420827 7 4 -DIHYDROXYFLAVON 10MM 1ML
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