Quinolines and derivatives
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Filtered Search Results
![eMolecules 166388-57-4 | Azido-PEG2-amine | Broadpharm | MFCD13189985 | 174.204 | C6H14N4O2 | 98.000 | NCCOCCOCCN=[N+]=[N-] | 5g | 229582910](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
eMolecules 166388-57-4 | Azido-PEG2-amine | Broadpharm | MFCD13189985 | 174.204 | C6H14N4O2 | 98.000 | NCCOCCOCCN=[N+]=[N-] | 5g | 229582910
Azido-PEG2-amine | Broadpharm | 166388-57-4 | MFCD13189985 | 174.204 | C6H14N4O2 | 98.000 | NCCOCCOCCN=[N+]=[N-] | 5g | 229582910
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Medchemexpress LLC Amino-PEG12-amine | 361543-12-6 | HY-133327 | 99.9% | 588.73 | 250 MG
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Amino-PEG12-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are molecules with two different ligands connected by a linker: one for an E3 ubiquitin ligase and another for a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used as a PEG-based PROTAC linker
- Enables synthesis of PROTACs
- Facilitates selective degradation of target proteins
- Appears as a colorless to off-white solid-liquid mixture
- Has a purity of 99.92%
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eMolecules 58794-09-5 | 7-bromoisoquinoline | Pharmablock | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 10g | 551259465
7-bromoisoquinoline | Pharmablock | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 10g | 551259465
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Medchemexpress LLC Mpeg-amine (mw 5000) | 80506-64-5 | 99.6% | (C2H4O)nC3H9NO | 100 MG
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mPEG-amine (mPEG-NH2) (MW 5000) is a modifier used to increase the water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes by replacing their sulfonic acid portion. It can also form amide bonds with carboxyl groups on the surface of microspheres under the mediation of EDC and Sulfo-NHS.
- Increases water solubility of dyes
- Forms amide bonds with carboxyl groups
- Suitable for large-scale rotational cytoplasmic flow studies
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eMolecules 4965-36-0 | 7-bromoquinoline | Pharmablock | MFCD03695823 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2cccnc2c1 | 2.5g | 686944591
7-bromoquinoline | Pharmablock | 4965-36-0 | MFCD03695823 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2cccnc2c1 | 2.5g | 686944591
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Medchemexpress LLC 3,6,9,12,15,18,21,24-octaoxapentacosan-1-amine | 869718-81-0 | >98.0% | 383.48 | C17H37NO8 | 500 MG
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m-PEG8-Amine is a cleavable polyethylene glycol (PEG8) linker with a terminal primary amine used for conjugation in antibody-drug conjugates (ADCs) and other bioconjugation chemistries for research applications.
- Cleavable ADC linker with PEG8 spacer and terminal primary amine for conjugation.
- High purity: >98.0%.
- Molecular weight 383.48 g/mol and formula C17H37NO8.
- Suitable for ADC and PROTAC linker synthesis and bioconjugation research.
- Available as 500 MG pack for laboratory use.
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Medchemexpress LLC Azido-PEG10-amine | 912849-73-1 | ≥97.0% | C22H46N4O10 | 250 MG
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Azido-PEG10-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This click chemistry reagent contains an Azide group, enabling participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker for PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups
- Supports strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
- PROTACs degrade target proteins via the ubiquitin-proteasome system
- Appearance is colorless to off-white
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Medchemexpress LLC Benzyl-PEG2-amine | 1268135-96-1 | C11H17NO2 | 1 G
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Benzyl-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Connects ligands for E3 ubiquitin ligase and target proteins
- Utilizes the ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Amino-PEG7-amine | 332941-25-0 | 99.3% | C16H36N2O7 | 100 MG
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Amino-PEG7-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This mechanism allows PROTACs to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. It is intended for research use only.
- Utilized in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Intended for research use only
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Medchemexpress LLC DBCO-amine | 1255942-06-3 | 99.1% | 276.34 g·mol-1 | C18H16N2O | 25 MG
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DBCO-amine is a dibenzocyclooctyne-containing amine reagent used for strain-promoted alkyne-azide cycloaddition (SPAAC) click chemistry. It is used as a small linker for bioconjugation and the synthesis of antibody-drug conjugates, and is typically handled and stored under anhydrous conditions and in organic solvent solutions for formulation.
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) bioconjugation.
- High purity suitable for synthetic and bioconjugation applications.
- Minimal spacer length reduces steric hindrance in conjugates.
- Compatible with common coupling chemistries for linker installation.
- Soluble in DMSO for straightforward formulation and handling.
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Cayman Chemical 8 12isoiPF2aVId11
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An internal standard for the quantification of 8,12-iso-iPF2α-VI by GC- or LC-MS.
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Medchemexpress LLC L-Cystathionine dihydrochloride | 61125-50-6 | 295.18 | 5 MG
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L-Cystathionine dihydrochloride is a nonprotein thioether and a key amino acid involved in the metabolic state of sulfur-containing amino acids. It has been shown to protect against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). This suggests an important role for L-Cystathionine in cardiovascular protection.
- Key amino acid associated with the metabolic state of sulfur-containing amino acids
- Protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs)
- Plays an important role in cardiovascular protection
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eMolecules 99584-10-8 | 6-Amino-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one | ChemScene | MFCD07801206 | 164.164 | C8H8N2O2 | 95.000 | Cn1c2ccc(N)cc2oc1=O | 250mg | 680025320
6-Amino-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one | ChemScene | 99584-10-8 | MFCD07801206 | 164.164 | C8H8N2O2 | 95.000 | Cn1c2ccc(N)cc2oc1=O | 250mg | 680025320
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Sigma Aldrich Fine Chemicals Biosciences 6-Aminoquinoline 98% | 580-15-4 | MFCD00006803 | 1G
6-Aminoquinoline 98% | Purity: 98% | Mol Wt: 144.17 | 580-15-4 | MFCD00006803 | 1G
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Medchemexpress LLC 2-(2-methoxyethoxy)ethanamine | 31576-51-9 | MFCD09032941 | 99.9% | 119.16 g/mol | C5H13NO2 | 1 G
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m-PEG2-Amine is a methoxy-terminated polyethylene glycol (PEG2) linker bearing a terminal primary amine used for bioconjugation and medicinal chemistry. It is commonly employed as a PEG-based PROTAC linker and as a cleavable linker in antibody-drug conjugate (ADC) synthesis.
- Methoxy-terminated PEG2 spacer with a terminal primary amine.
- Suitable for PROTAC synthesis and as a cleavable ADC linker.
- Hydrophilic spacer improves solubility and flexibility of conjugates.
- High purity for reliable conjugation reactions.
- Store at 4°C and protect from light; in solution, store long-term at -80°C.
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